Dona ganguly biography definition

Abstract

Bundled with various kinds of adhesion molecules and anchored to the basement membrane, the epithelium has historically been considered as an immotile tissue and, to migrate, it first needs to undergo epithelial-mesenchymal transition (EMT). Since its initial description more than half a century ago, the EMT process has fascinated generations of developmental biologists and, more recently, cancer biologists as it is believed to be essential for not only embryonic development, organ formation, but cancer metastasis. However, recent progress shows that epithelium is much more motile than previously realized. Here, we examine the emerging themes in epithelial collective migration and how this has impacted our understanding of EMT.

Keywords: cell polarity, epithelial polarity, apicobasal polarity, collective migration, EMT, extracellular matrix, mechanosensing, mesenchymal-epithelial transition

Introduction

The emergence of the epithelium is one of the earliest and most important events during metazoan evolution. By separating an organism from the outside world, the epithelium protected cells within the organism from environmental insults and facilitated the rise and prosperity of multicellularity. Far from being a simple, protective shield or barrier, the epithelium also allowed an organism to actively exchange substances, including nutrients, wastes, gases, etc. with the environment, a basis on which organ systems, including the digestive, respiratory, urinary, and glandular systems emerged during evolution. These organ systems enabled the metazoans to explore previously untapped niches and, eventually, to dominate almost every corner of the planet earth (Dickinson et al., 2011). Today, most major organs of extant animals are epithelial and most human cancers are of epithelial origin, thus highlighting the importance of epithelial function in physiology and pathology.

Historically, the epithelium i

Former Indian Cricket player and Captain of the Indian national cricket team, Sourav Ganguly, also known as the ‘Dada’ or ‘Prince of Calcutta’. He was born on 7th July 1982, in the city of Kolkata. His parents lived in a locality called Behala in Kolkata. His mother’s name was Nirupa Ganguly, and his father’s name was Chandidas Ganguly. Left-handed Ganguly was a right-handed medium-fast bowler. At present, Ganguly is the President of BCCI. He was known to be an aggressive and successful captain.

Formative Days

They were two brothers, Snehashis Ganguly, the elder brother, and Sourav Ganguly, the younger brother. Their father was in the business of printing and was one of the richest people in Kolkata. They had a rich upbringing and were never short on resources.

One of his childhood nicknames was ‘Maharaja’, meaning’ the Great king’. As most people of Kolkata love the game of football, so did Sourav Ganguly. He was earlier inclined towards football, and his studies were hampered. His mother was strictly against him joining any kind of sport. His elder brother was already an established cricketer playing for the Bengal cricket team. With his support, Sourav started his career and later got his dream of becoming a cricketer fulfilled. 

In his 10th standard, Sourav, with his father’s permission, got enrolled in a cricket coaching camp during the summer holidays. Left-handed Ganguly excelled in cricket as a left-handed batsman. When he made his debut on the state team, his brother was dropped from the state team. His father expired in 2013, on the 21st Feb at the age of 73. After England’s successful tour, he married his childhood love, Dona Roy.    

Cricket Career Journey

Apart from being a good left-handed batsman, he was also a very thoughtful bowler. He was a fluent driver on the Offside in batting, so he was also called the ‘God Of The Off Side’. Af

Indian cricketer

Sourav Chandidas Ganguly (; natively spelled as Gangopadhyay; born 8 July 1972), also known as Dada (meaning "eld